Jennifer Aniston's disclosure about using NAD+ IV drips during an interview with The Wall Street Journal last year sparked a surge of interest on the internet regarding this supplemental therapy. This treatment claims to enhance energy levels and skin quality. With increasing demand, NAD+ is transitioning from clinical settings to oral supplements and skincare products, presenting fresh avenues for beauty brands to explore.
NAD, a coenzyme present in all cells of the body, is crucial for preserving cellular well-being. Nevertheless, its levels decrease as we age, leading to reduced cellular function, which can result in inflammation and hastened aging processes.
NAD+ has garnered a significant following, including among healthcare professionals. Dr. David Jack, an aesthetic doctor, surgeon, and the creator of his own skincare line, describes NAD+ as "a critical factor in preserving cellular equilibrium and longevity." Dr. Jinah Yoo, a dermatologist on Harley Street, further explains that the diminishing levels of NAD+ can lead to vulnerabilities in the skin barrier, resulting in issues like moisture loss, redness, irritation, and inflammatory conditions.
With NAD+ transitioning from celebrity and biohacking spheres to broader acceptance, wellness and beauty companies are investigating methods to incorporate it into oral supplements or skincare items. Dr. Nathan Curran, a medical professional, notes, "NAD+ presents a highly appealing proposition for brands, as it addresses various aging-related factors by combating inflammation."
Nevertheless, experts caution brands to prioritize effectiveness when incorporating NAD+ into skincare products. Dr. Jack highlights, "Although topical NAD+ holds promise for aging skin, its effectiveness greatly depends on factors like formulation stability, skin absorption, and concentration."
Rhian Stephenson, the creator of the supplement brand Artah, who is also a nutritionist and naturopath, emphasizes that the effectiveness of any NAD+ product relies on the individual's health status. Factors such as chronic stress, overeating, excessive alcohol consumption, an unhealthy diet, smoking, and inadequate sleep can diminish NAD+ levels.
Companies such as Artah and Victoria Health incorporate essential components that the body can transform into NAD+, referred to as NAD+ precursors. Shabir Daya, co-founder of Victoria Health and a pharmacist, explains, "NAD+ supplements cannot effectively elevate NAD+ levels without precursors because of the size of the NAD molecule and the body's incapacity to directly absorb it into the bloodstream."
To navigate concerns regarding product effectiveness, Dr. Jack advises up-and-coming brands to incorporate ingredient enhancers into their formulations. "Utilizing nanoparticles, synthetic lipid particles, or oleic acid could enhance the penetration of NAD+ and its precursors into the skin," he suggests.
Anticipated by experts, the increasing prominence of NAD+ aligns with the emphasis on healthy aging and longevity, fostering ongoing advancements. Dr. Curran foresees that NAD+ will gain more recognition in 2024 and beyond as a pivotal ingredient in addressing inflammation, potentially joining the ranks of traditional skincare essentials like collagen, vitamin C, and SPF.